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Redcliffe Genetics

Redcliffe Genetics, a unit of Redcliffe Labs, is India's fastest growing Genomics and integrated research organization to provide widest range of genomics services coupled with advanced bioinformatics analysis for healthcare companies, research institutions, other public and private partnerships across the globe.

We are the only lab in South Asia with Illumina Novaseq 6000, Nanostring’s GeoMx Digital Spatial Profiler (DSP), Oxford Nanopore, Nanostring’s nCounter to measure gene expression, MGI DNB and PacBio under the same roof.

Applications & services


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Departments & Research Areas

Plant Science and Research

Agriculture is the science of farming plants and animals for food, fiber, and fuel. The impact of population pressure on agricultural land and livestock towards food sufficiency is already enormous. Degradation of lands, soils and water scarcity is aggravating the existing situation. Harnessing genomics innovations in agriculture has become an absolute necessity, as it only can address and sustainably cater to these challenges such as changing environment, expanding population, and increasing demands for nutrition. As genomics becomes more widely used in agriculture, researchers and breeders are increasingly using NGS and microarray approaches to drive discoveries and advances.

Cancer Research

A wide range of mutations, epigenetic changes and gene expression alterations are known to be involved in the progression of various cancers.

NGS methods provide deep insights into the genomes of cancers as they can detect somatic variants, tumor subclones, and circulating DNA fragments with increased sensitivity. Known as well as novel genetic aberrations and gene expression changes can be uncovered using whole genome and whole exome sequencing approaches.

This way a comprehensive view of the unique mutations and genomic alterations in cancer tissue can be obtained, including those contributed by surrounding normal tissue and tumor clonality.

Human Genomics

The Human Genome Project is one of the greatest scientific feats in history. It was a landmark global scientific effort whose signature goal was to generate the first sequence of the human genome. With advances in sequencing technologies, Next-generation sequencing is becoming the primary discovery tool in human genetics.

NGS has helped in successful identification of genes that are responsible for various Mendelian diseases as well as identification of mutations that cause undiagnosed childhood genetic diseases and those that predispose individuals to more common complex diseases. Genome-wide association studies (GWASs) have been successful in identifying genomic regions that influence the risk of human complex disease as well as in variant calling and annotation studies.

Population Genetics

Sequencing the DNA or mRNA of multiple individuals of one or more species is termed as population-scale sequencing. It aims to identify genetic variation at a population level to address questions in the fields of evolutionary, agricultural and medical research.

High-throughput sequencing technologies have provided an unprecedented opportunity to study the different evolutionary forces that have shaped present-day patterns of genetic diversity.

Furthermore, with the advent of Long-read sequencing technologies, we have now reached a level of accuracy and yield that allows their application to variant detection at a scale of tens to thousands of samples.

Animal Science and Research

NGS technologies are useful for studying various aspects of animal genomics, including genotype, gene expression and regulation, and epigenetics. These approaches offer the throughput, sensitivity, and precision needed to evaluate genetic markers and discover new ones associated with traits or disease.

Moreover, an accurate view of the genetic influence on traits and diseases is crucial for breeders develop healthier and more productive livestock. NGS provides a high-resolution view of the genetic variation influencing phenotype in animals which s useful for discovering novel markers..

Microarrays offer a cost-effective solution for analyzing large sample numbers in routine screening applications.

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