Chip Sequencing

ChIP Sequencing is useful to identify Genome-wide binding sites for transcription factors and other DNA binding proteins.

It involves crosslinking of DNA-protein complexes followed by immunoprecipitation with a specific antibody. The captured DNA is then coprecipitated, purified and sequenced.

ChIP helps to gain insights into the epigenetic gene regulation events that play pivotal roles in various diseases and biological pathways, such as development and cancer progression.